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fi- lactam antibiotics specifically bind to the ___________ that are essential in cell wall formation.

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penicillin...

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The process by which macromolecules lose their structure and ability to function is called


A) thermal death.
B) sterilization.
C) denaturation.
D) none of the above.

E) A) and B)
F) All of the above

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Write a succinct definition of an antibiotic, and explain why this is an apt term, quite distinct from straight chemical antimicrobics.

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An antibiotic is a chemical substance pr...

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Many countries, such as Australia, France, Germany, and the United States, decontaminate and sterilize certain foods with ionizing radiation.

A) True
B) False

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Neuraminidase inhibitors such as oseltamivir and zanamivir are used to treat which type of infection?


A) fungal
B) influenza virus
C) parasitic
D) bacterial

E) A) and B)
F) A) and C)

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Semisynthetic antibiotics


A) are natural antibiotics that have been purified by artificial means.
B) are natural antibiotics that have been chemically modified in the laboratory.
C) have an artificially constructed core that stimulates the production of "natural products."
D) are found in nature, but their rate of production is enhanced in the laboratory.

E) C) and D)
F) A) and B)

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The most successful agents used for antiviral chemotherapy are


A) nucleotide analogs.
B) protein synthesis inhibitors.
C) nucleoside analogs.
D) ATP reductase inhibitors.

E) B) and D)
F) A) and D)

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The time required for a tenfold reduction of the viability of a microbial population at a given temperature is called the__________time.


A) mean sterilization
B) temperature- dependent logarithmic death
C) thermal death
D) decimal reduction.

E) B) and D)
F) B) and C)

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Both cephalosporins and penicillins have the same mode of action, despite the two having different chemical structures.

A) True
B) False

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Like erythromycin and the aminoglycosides, __________inhibits protein synthesis.

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A__________ filter is most often used to filter sterilize liquids.


A) membrane
B) microbistat
C) depth
D) nucleation track

E) A) and D)
F) B) and D)

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Explain what is meant by selective toxicity. How does selective toxicity relate to the development of chemotherapeutic agents?

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Selective toxicity is the idea that only...

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The production of interferon is stimulated by the presence o__________f , which signals a virus infection in an animal cell.

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Because of their limited range of effectiveness, the fluoroquinolones are used primarily in treating infections caused by gram- positive Bacteria.

A) True
B) False

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Compared with decontamination, disinfection is


A) less aggressive.
B) equally aggressive.
C) more aggressive.
D) either more or less aggressive, depending on the situation in question.

E) A) and D)
F) A) and C)

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The__________ involves a lawn of bacteria on an agar plate exposed to small discs containing known amounts of antimicrobial agents.

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disk diffu...

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A___________ filter is most often used in scanning electron microscopy.


A) microbistat
B) depth
C) nucleation track
D) membrane

E) A) and B)
F) A) and C)

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Pathogens are often encased and grow in large numbers as__________ , covering the surfaces of tissues or medical devices with several layers of microbial cells.

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Highly active anti- retroviral therapy (HAART) , which involves a combination of nucleoside analogs and protease inhibitors, is most commonly used to treat infections of


A) HIV.
B) drug resistant strains of bacteria.
C) Mycobacterium tuberculosis.
D) Staphylococcus aureus.

E) A) and C)
F) B) and C)

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Growth factor analogs that resemble nucleic acids are used in the treatment of viral and fungal infections.

A) True
B) False

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